Oral Session.indd

Design and method: The animal model chosen was a murine model developing metabolic syndrome. Mice received during a year, a high fat diet or a control diet. Systolic blood pressure and heart rate measurements were performed and the determination of metabolic parameters was performed. The Visualsonicsâ, a small animal echocardiography system, was used to study cardiac function and left ventricular dimensions. MicroPET (positron emission tomography) experiments were done in parallel for studying the metabolism. Finally the MRI (Magnetic resonance imaging) technique was used to locate the interscapular brown fat and determine the water ratio on fat for each animal.